In patients who have P.A.D. PLAVIX Can Help Reduce Your Risk of Heart Attack or Stroke
P.A.D. is a serious condition that more than doubles your risk
of a heart attack or stroke. So, if you have been diagnosed with P.A.D., talk to
your doctor as soon as possible about starting treatment to reduce your risk. For many patients like you who have P.A.D., antiplatelet medications like PLAVIX may help protect against a heart attack or stroke. PLAVIX is a prescription antiplatelet medication that helps keep blood platelets from sticking together and forming clots. It is approved by the FDA to reduce the risk of heart attack or stroke in people who've been diagnosed with P.A.D.

PLAVIX can help keep you protected
If you are prescribed an antiplatelet medication like PLAVIX for your P.A.D., it means
your doctor knows you are at an increased risk for heart attack and strokeāa risk
that doesn't go away. Remember:
- PLAVIX can only help protect from a heart attack or stroke as long as you keep taking it.
- Take PLAVIX exactly as your doctor tells you.
- Do not change your dose or stop taking PLAVIX without talking to your doctor first. Stopping PLAVIX may increase your risk of heart attack or stroke.
Remember to discuss questions or concerns about your antiplatelet medicine directly
with your doctor.

PLAVIX works differently than other medications
If you have been diagnosed with P.A.D., your doctor may prescribe a treatment for your leg pain.* You may also be taking medicines to help lower your cholesterol or blood pressure to help reduce your risk of a heart attack or stroke. PLAVIX works differently by helping to reduce your risk of a future heart attack or stroke by keeping blood platelets from sticking together and forming clots.
Always talk to your doctor before taking aspirin or other medicines with PLAVIX, especially if you’ve had a stroke. See how different cardiovascular and heart medications work using the Understanding Heart Medications Chart.
As an antiplatelet medication, PLAVIX works differently than other medicines by
helping to prevent the formation of clots, the cause of most heart attacks and
strokes. Medical guidelines recommend that patients with P.A.D. get therapy to
help reduce clot formation in addition to their other cardiovascular
risk-reducing medications.
*PLAVIX is not indicated for the treatment of symptoms of P.A.D. PLAVIX helps keep blood platelets from sticking together and forming clots, the cause of most heart attacks and strokes.

IMPORTANT SAFETY INFORMATION
Certain genetic factors and some medicines such as Prilosec reduce the effect of PLAVIX leaving you at greater risk for heart attack and stroke. Your doctor may use genetic tests to determine treatment. Don’t stop taking PLAVIX without talking to your doctor as your risk of heart attack or stroke may increase. People with stomach ulcers or conditions that cause bleeding should not use PLAVIX. Taking PLAVIX alone or with some other medicines, including aspirin, may increase bleeding risk which can potentially be life-threatening. So tell your doctor when planning surgery. Tell your doctor all medicines you take, including aspirin, especially if you’ve had a stroke. If fever, unexplained weakness or confusion develops, tell your doctor promptly. These may be signs of TTP, a rare but potentially life-threatening condition, reported sometimes less than 2 weeks after starting PLAVIX.
Click here for US Full Prescribing Information Including BOXED WARNING
and Medication Guide
Remember, your doctor is the single best source of information regarding your health. Please consult your doctor if you have any questions about your health or your medicine.
What to do next: Learn if you need to improve blood circulation